GO:0003712 molecular_function transcription coregulator activity
| PAG Title | GO:0003712 molecular_function transcription coregulator activity |
| PAG ID | TAX014771 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators. |
| Species | Homo sapiens |
| nCoCo Score | 507 |
| Base PAG ID | TAX014771 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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